Try handling the grid.Model.QueryCellInfo event.
In your handler, if e.RowIndex > 0 and if e.ColIndex points to one of the ''next two cells'' you mentioned, then get the value of the comboxcell and set e.Style.Enabled accordingly.
private void Model_QueryCellInfo(object sender, GridQueryCellInfoEventArgs e)
{
if(e.RowIndex > 0)
{
if(e.ColIndex == this.grid.Binder.NameToColIndex("NextCol1")
|| e.ColIndex == this.grid.Binder.NameToColIndex("NextCol2"))
{
int col = this.grid.Binder.NameToColIndex("ComboCol");
string val = this.grid[e.RowIndex, col].Text; //may want .FormattedText
if(val == "NextYear")
e.Style.Enabled = true;
else
e.Style.Enabled = false;
}
}
}