PrepareViewStyleInfo is the place you need to do this. I think you have to be more careful with teh indexes. If you want to reference 2 coluns prior, then the current column must be greater than 2 for this to make sense. Here is a try at this using aribitray rows > 0.
Private Sub mysched_PrepareViewStyleInfo(ByVal sender As Object, ByVal e As GridPrepareViewStyleInfoEventArgs) Handles mySched.PrepareViewStyleInfo
If e.RowIndex > 0 And e.ColIndex > 2 Then
if( e.Style.CellValue.ToString.StartsWith("A") Then
If CInt(mySched.Model(e.RowIndex, e.ColIndex - 2).CellValue.ToString.Substring(10)) < CInt(e.Style.CellValue.ToString.Substring(8)) Then
e.Style.BackColor = Color.green
End If
End If
End If
end sub