Can a WPF application be designed using Microsoft Expression Blend ?

Yes. WPF application can be created using Expression Blend. When an object is placed, it automatically creates it’s corresponding XAML code and when saved, .csproj is created. This file can then be opened using the Visual Studio.NET and other procedural coding can be added. Similarly a WPF application created using the Visual Studio.NET can be opened using Expression Blend to apply design changes.